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Hypersensitivity against fluoxetine.
MAO inhibitors: Concomitant use of fluoxetine and MAOI should be avoided. Due to experience with the simultaneous administration of MAO-inhibitors and tricyclic antidepressants a period of at least 14 days should be chosen after the discontinuation of the MAOI and the onset of the fluoxetine therapy. Due to the long half-life of fluoxetine and the active metabolite norfluoxetine a period of at least 5 weeks (about 5 half-lives of norfluoxetine) should be chosen after the discontinuation of fluoxetine and the onset of the therapy with MAOI. The administration of MAOI within 5 weeks after the discontinuation of fluoxetine may increase the risk of severe adverse events.
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