Doxar Dosage/Direction for Use

Losartan may be administered with or without food and together with other antihypertensive agents.
The usual dose for hypertension is 50 mg once daily for most patients. The maximal antihypertensive effect is attained 3-6 weeks after initiation of therapy. Dose may be increased, to 100 mg once daily as a single dose or in two divided doses. A low dose of a diuretic may be added if blood pressure is not controlled by losartan alone. Hydrochlorothiazide has been shown to have an additive effect.
It may be prudent to start with 25 mg once daily in patients with possible intravascular volume depletion (e.g. patients treated with diuretics), and in patients with hepatic impairment. Similar reduction may be appropriate in patients with hepatic or renal impairment.
In the elderly over 75 years and for patients with moderate to severe renal impairment (creatinine clearance less than 20 mL per minute), the dose is started at 25 mg once daily.
Or as prescribed by the physician.