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ORAL: Unstable Angina Pectoris including Angina Due to Coronary Artery Spasm or Following Myocardial Infarction: Diltiazem is indicated for the treatment of angina pectoris due to coronary artery spasm. Diltiazem has been shown to be effective in the treatment of spontaneous coronary artery spasm presenting as Prinzmetal's variant angina (resting angina with ST-segment elevation occurring during attacks).
Chronic Stable Angina (Classic Effort-associated Angina): Diltiazem is indicated for the management of chronic stable angina in patients who cannot tolerate therapy with beta-blockers and/or nitrates or who remain symptomatic despite adequate doses of these agents.
Hypertension: Diltiazem is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive medications, such as diuretics.
Kidney Transplantation: Diltiazem is indicated for the prevention of graft failure following kidney transplantation. Diltiazem is indicated for the reduction of ciclosporin A nephrotoxicity during immunosuppressive therapy after kidney transplantation.
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