Diatabs Advance Contraindications

If the patient is allergic to loperamide or simeticone or any ingredient in the product.
If the patient's abdomen is swollen.
If the patient has abdominal pain in the absence of diarrhea.
If the patient has acute dysentery which is characterized by bloody stools and fever.
If the patient has pseudomembranous ulcerative colitis (diarrhea associated with antibiotics), acute ulcerative colitis (inflammation of the colon), bacterial enterocolitis (inflammation of the digestive tract resulting from bacterial infection such as Salmonella, Shigella, and Campylobacter).
If a child is under 12 years old.
If the patient is constipated and in cases when constipation should be avoided (e.g., diarrhea resulting from infections).
If the patient has difficulty swallowing.
Loperamide + simeticone should not be used in medical conditions where slowing of the intestines should be avoided due to the possible risk of developing ileus (blockage of the intestine), megacolon (acute dilatation of the colon) and toxic megacolon (acute dilatation of the colon associated with infection or inflammation).
Loperamide + simeticone should be discontinued immediately when constipation, abdominal distension, or ileus (blockage of the intestine) develop.