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There have been no reports of significant overdose with Dexlansoprazole (Dexilant). Multiple doses of Dexlansoprazole (Dexilant) 120 mg and a single dose of Dexlansoprazole (Dexilant) 300 mg did not result in death or other severe adverse events. However, serious adverse events of hypertension have been reported in association with twice daily doses of Dexlansoprazole (Dexilant) 60 mg. Nonserious adverse reactions observed with twice daily doses of Dexlansoprazole (Dexilant) 60 mg include hot flashes, contusion, oropharyngeal pain, and weight loss. Dexlansoprazole is not expected to be removed from the circulation by hemodialysis.
In the event of over-exposure, treatment should be symptomatic and supportive.
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