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Pregnancy: There are no or limited amount of data from the use of Dexamethasone + Neomycin (as sulfate) + Polymyxin-B-Sulfate (Dexatrol) in pregnant women.
Studies in animals with some active components of Dexamethasone + Neomycin (as sulfate) + Polymyxin-B-Sulfate (Dexatrol) have shown reproductive toxicity. Dexamethasone + Neomycin (as sulfate) + Polymyxin-B-Sulfate (Dexatrol) is not recommended during pregnancy.
Lactation: It is unknown whether topical ophthalmic dexamethasone, neomycin or polymyxin B are excreted in human milk. Because systemic corticosteroids and aminoglycosides may be distributed into milk, a risk to the suckling child cannot be excluded.
A decision must be made whether to discontinue breast-feeding or to discontinue therapy with Dexamethasone + Neomycin (as sulfate) + Polymyxin-B-Sulfate (Dexatrol) taking into account the benefit of breast-feeding for the child and the benefit of the product to the woman.
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