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Cosmox: Adult and children ≥40 kg: 625 mg every 12 hours or 375 mg every 8 hours.
More severe & respiratory tract infections 625 mg every 8 hours.
Severely impaired patients w/ GFR 10-30 mL/min: 625 mg or 375 mg every 12 hours, depending on the severity of the infection;
<10 mL/min GFR 625 or 375 every 24 hours depending on severity of the infection.
Ped ≥40 kg Adult dose.
Cosmox 457: Children under 12 months 25 mg/kg/day e.g., a 7.5 kg child would require 2 mL three times a day.
Children 1-6 years (10-18 kg) 5 mL suspension three times a day.
Children over 6 years (18-40 kg) 5 mL suspension three times a day. In severe infections this may be increased up to 50 mg/kg/day in divided doses every eight hours.
Or as prescribed by the physician.
Direction for reconstitution: Slowly add 64 mL of water to make 70 mL of the suspension. Shake vigorously.
After reconstitution keep the suspension in the refrigerator 2-8°C when not in use.
Use the reconstituted suspension within 7 days.
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