Concomitant administration of clopidogrel with NSAIDs is associated with increased occult gastrointestinal blood loss. Therefore, NSAIDs and clopidogrel should be coadministered with caution. Clopidogrel may interfere with the metabolism of phenytoin, tamoxifen, tolbutamide, warfarin, torsemide, fluvastatin, and therefore, should be, coadministered with caution.