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It is recommended that agents which affect hemostasis should be discontinued prior to enoxaparin sodium therapy unless strictly indicated. These agents include medications such as: Systemic salicylates, acetylsalicylic acid, and NSAIDs including ketorolac; Dextran 40; ticlopidine and clopidogrel; Systemic glucocorticoids; Thrombolytics and anticoagulants; Other anti-platelet agents including glycoprotein IIb/IIIa antagonists.
If the combination is indicated, enoxaparin sodium should be used with careful clinical and laboratory monitoring when appropriate.
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