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Amlodipine should be used with caution in patients with hypotension, in patients whose cardiac reserve is poor, and in those with heart failure since deterioration of heart failure has been noted.
Amlodipine half-life is prolonged in patients with hepatic impairment, may need dose reduction.
Use in Pregnancy & Lactation: Amlodipine safety in pregnancy has not been established. Used during pregnancy only if the potential benefit outweighs the potential risk to the mother and fetus, but if possible avoid during pregnancy.
It is not known whether amlodipine is excreted in human milk. However, amlodipine safety in infants has not been established. Advise not to be given to nursing mothers.
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