Bizyx Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Biperiden HCl

Indications/Uses

Symptomatic treatment of parkinsonism including alleviation of extrapyramidal syndrome induced by drugs eg, phenothiazines.

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Dosage/Direction for Use

Parkinson's disease Initially 2 mg tid or qid, increased according to response to max of 16 mg daily. Drug-induced extrapyramidal symptom 2 mg once daily to tid.

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Overdosage

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Administration

Should be taken with food.

Contraindications

Hypersensitivity. Narrow angle glaucoma; bowel obstruction; megacolon.

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Special Precautions

Not to be given to patients w/ angle-closure glaucoma or w/ narrow angle between the iris & the cornea. Isolated instances of mental confusion, euphoria, agitation & disturbed behaviour. Risk of central anticholinergic syndrome. Patients w/ manifest glaucoma; prostatism, epilepsy or cardiac arrhythmia; acute MI & HTN. May raise IOP & precipitate acute attack. Caution in conditions characterized by tachycardia eg, thyrotoxicosis, heart failure, & in cardiac surgery. May cause confusion. Reduced bronchial secretion. Avoid abrupt w/drawal. Avoid consumption of alcohol during therapy. Drowsiness may occasionally occur which may affect ability to drive or operate machinery. Pregnancy & lactation. Safety & effectiveness have not been established in childn. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Dryness of mouth w/ difficulty in swallowing & talking, thirst, reduced bronchial secretions, mydriasis w/ cycloplegia & photophobia, flushing & dryness of skin, transient bradycardia followed by tachycardia w/ palpitations & arrhythmias, difficulty in micturition, reduction in tone & motility of the GIT leading to constipation.

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Drug Interactions

Effects may be enhanced w/ other drugs w/ antimuscarinic properties eg, amantadine, some antihistamines, phenothiazine, antipsychotics, & TCAs; MAOIs. May antagonize GI effects of cisapride, domperidone, & metoclopramide. Concomitant use w/ parasympathomimetics may counteract each other's effects

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Storage

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Description

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Action

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MIMS Class

Antiparkinsonian Drugs

ATC Classification

N04AA02 - biperiden ; Belongs to the class of tertiary amines anticholinergic agents. Used in the management of Parkinson's disease.

Regulatory Classification

Presentation/Packing

Form

Bizyx tab 2 mg

Packing/Price

100's

Bizyx

biperiden

Manufacturer:

Lloyd

Distributor:

InnoGen Pharmaceuticals