Usual Dose: Hydrocortisone 100-500 mg, repeated 3-4 times in 24 hrs, according to the severity of the conditions and the patient's response.
Children <1 Year: 25 mg. 1-5 Years: 50 mg. 6-12 Years: 100 mg.
Administration: Given IV, by slow injection or infusion when a rapid effect is required in emergencies, such conditions are acute adrenocortical insufficiency caused by Addisonian or post-adrenalectomy crises, by the abrupt accidental withdrawal therapy in corticosteroid-treated patients, or by the inability of the adrenal glands to cope with increased stress in such patients and shock.
Fluids and electrolytes should be given as necessary to correct any associated metabolic disorder. Similar doses to those specified above may also be given IM but the response is likely to be less rapid than that observed following IV administration.
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