Betadine Dry Powder Spray Drug Interactions

Do not apply other medications to the same affected areas treated with POVIDONE-IODINE (BETADINE) dry powder spray, unless the doctor has told so.
The PVP-Iodine complex is effective at pH of between 2.0 and 7.0. It has to be expected that the complex will react with protein and other unsaturated organic compounds, leading to impairment of its effectiveness.
The concomitant use of other externally applied wound healing medicines/preparations may alter the effect of POVIDONE-IODINE (BETADINE) dry powder spray or both. Products containing enzymatic component, alkali, acetylsalicylic acid, bismuth, mercury, silver, hydrogen peroxide, tannic acid and taurolidine may interact with povidone-iodine and should not be used concomitantly.
Using this treatment may interfere with tests on thyroid function and can make a planned treatment of the thyroid with iodine impossible. After the end of the treatment an interval of at least 1-2 weeks should be allowed before a new scintigram is carried out.
Contamination with povidone-iodine of several types of tests for the detection of occult blood in feces or blood in urine may produce false-positive results.
It is not likely that other drugs taken orally or inject will have an effect on externally applied POVIDONE-IODINE (BETADINE) dry powder spray.
Povidone-Iodine products when used concomitantly or immediately after application of octenidine containing antiseptics in the same or adjacent sites may lead to transient dark discolorations in the areas involved.
Due to the oxidative effect of povidone-iodine preparations various diagnostic agents can show false-positive lab results (e.g., tests with toluidine or gum guaiac for the determination of hemoglobin or glucose in the stool or the urine).
Absorption of iodine from povidone-iodine solution may lower the iodine uptake of the thyroid can lead to interference with various investigations (thyroid scintigraphy, determination of PBI (protein-bound iodine), radioiodine diagnostics and can make a planned treatment of the thyroid with iodine (radioiodine therapy) impossible. After the end of the treatment, an appropriate interval should be allowed before a new scintigram is carried out.
Do not start a new treatment medication without telling the doctor. For more information about any other possible risks associated with POVIDONE-IODINE (BETADINE) dry powder spray, please consult the doctor or pharmacist.