Overdosage may lead to muscular hypotonia, hypothermia, drowsiness, respiratory depression, coma, and convulsions.
Treatment of Baclofen overdosage is symptomatic. Consideration should be given to the use of activated charcoal in adults who have ingested more than 100 mg and children who have taken more than 5 mg/kg, within an hour of presentation. Alternatively, gastric lavage may be considered in adults within an hour of ingesting a life-threatening overdose. Haemodialysis should be considered in severe cases.
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