Salbutamol and other beta agonists may cause fine tremor of skeletal muscle (particularly the hands), palpitations, tachycardia, nervous tension, headaches, peripheral vasodilation, and rarely muscle cramps.
Potentially serious hypokalaemia has been reported after large doses. Hypersensitivity reactions have occurred including paradoxical bronchospasm, angioedema, urticaria, hypotension and collapse.