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Telmisartan Drug Interactions: Lithium: Reversible increase in serum lithium concentration and toxicity have been reportedly during concomitant administration of lithium with angiotensin enzyme inhibitors, and with angiotensin II receptor antagonists, including telmisartan. If use of the combination proves necessary careful monitoring of serum lithium levels is recommended.
Aliskiren: Do not administered with Telmisartan and Amlodipine in patients with diabetes and renal impairment.
Digoxin: When telmisartan is co-administered with digoxin, median increases in digoxin peak plasma concentration (49%) and in trough concentration (20%) were observed.
Amlodipine Drug Interactions: Simvastatin: Co-administration of multiple doses of 10mg of amlodipine with 80mg of simvastatin resulted in a 77% increases in exposure to simvastatin compared to simvastatin alone. Limit the dose of simvastatin in patients on amlodipine 20mg daily.
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