Antaxid Dosage/Direction for Use

In the treatment of gastro-oesophageal reflux disease, the usual dose by mouth is 20 to 40 mg once daily for 4 weeks, increased to 8 weeks if necessary, in the USA, up to 16 weeks of therapy is permitted for healing erosive oesophagitis. For maintenance therapy, treatment can be continued with 20 to 40 mg daily. Alternatively, for recurring symptoms, an on-demand regimen of 20 mg daily may be given.
The usual dose for treatment of peptic ulcer disease is 40 mg once daily.
Treatment is usually given for 2 to 4 weeks of duodenal ulceration, or 4 to 8 weeks for benign gastric ulceration.
Patients who require prophylaxis for NSAID-associated ulceration may take 20 mg tablet.
In the treatment of pathological hypersecretory states such as Zollinger-Ellison syndrome, the initial dose is 80 mg daily, adjusted as required. Doses of up to 240 mg daily have been used. Daily doses greater than 80 mg should be given in 2 divided doses.
Doses of pantoprazole may need to be reduced in patients with hepatic impairment or as prescribed by the Physician.