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Oral: Usual adult dose: The dose is one tablet of 35 mg of Trimetazidine hydrochloride (ANGIREL MR) twice daily during meals.
Special populations: Patients with renal impairment: In patient with moderate renal impairment (creatinine clearance [30-60] mL/min), the recommended dose is 1 tablet of 35 mg in the morning during breakfast.
Elderly patients: Elderly patients may have increased Trimetazidine hydrochloride (ANGIREL MR) exposure due to age-related decrease in renal function. In patients with moderate renal impairment (creatinine clearance [30-60] mL/min), the recommended dose is 1 tablet of 35 mg in the morning during breakfast. Dose titration in elderly patients should be exercised with caution.
Pediatric population: The safety and efficacy of Trimetazidine hydrochloride (ANGIREL MR) in children aged below 18 years have not been established. No data are available.
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