Anazole Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Anastrozole

Indications/Uses

1st-line treatment of postmenopausal women w/ hormone receptor +ve or hormone receptor unknown locally advanced or metastatic breast cancer. Advanced breast cancer in postmenopausal women w/ disease progression after tamoxifen therapy. Adjuvant treatment of postmenopausal women w/ hormone receptor +ve early breast cancer.

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Dosage/Direction for Use

1 tab once daily.

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Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Premenopausal women. Severe renal failure; moderate or severe hepatic failure. Concomitant use of selective estrogen receptor modulators & other aromatase inhibitors. Pregnancy & lactation. Childn.

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Special Precautions

Postmenopausal women at high risk for osteoporosis. Monitor serum lipoprotein conc for long-term therapy. Patients w/ osteoporosis or osteopenia. May impair ability to drive or operate machinery. Childn <18 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

CV, genitourinary, musculoskeletal, GI, resp, CNS, dermatologic, hepatic & hematologic effects. Wt loss/gain, cataracts, asthenia, nonspecific pain, chest pain (nonspecific), flu syndrome, accidental injury, lethargy, fever & malaise.

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Drug Interactions

Selective estrogen receptor modulators (eg, tamoxifen, raloxifene) & aromatase inhibitors (eg, exemestane, formestane, letrozole). Action may be diminished by estrogens. May inhibit in vitro metabolic reactions catalyzed by cytochrome P-450 isoenzymes 1A2, 2C8/9 & 3A4 (but only at high conc).

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Description

View Anazole description for details of the chemical structure and excipients (inactive components).

Action

View Anazole mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Cancer Hormone Therapy

ATC Classification

L02BG03 - anastrozole ; Belongs to the class of enzyme inhibitors. Used in treatment of neoplastic diseases.

Regulatory Classification

Presentation/Packing

Form

Anazole tab 1 mg

Packing/Price

28's (P4,620/pack)

Anazole

anastrozole

Manufacturer:

UNILAB, Inc

Distributor:

UNILAB, Inc