Amena Dosage/Direction for Use

Tibolone is a steroid derived from noretynodrel that has oestrogenic, progestogenic, and weak androgenic properties. The usual dose is 2.5 mg daily by mouth. Tibolone reduces vasomotor symptoms associated with the use of gonadorelin analogues for endometriosis or fibroids.
Starting Tibolone: Women experiencing a natural menopause should commence treatment with tibolone at least 12 months after their last menstrual bleed. In case of surgical menopause, treatment with Tibolone, may commence immediately.
Switching from a sequential or continuous combined HRT preparation: If changing from a sequential HRT preparation, treatment with Tibolone should start the day following completion of the prior regimen. If changing from a continuous-combined HRT preparation, treatment can start at any time.
Missed dose: A missed dose should be taken as soon as remembered, unless it is more than 12 hours overdue. In the latter case, the missed dose should be skipped and the next dose should be taken at the normal time. Missing a dose may increase the likelihood of breakthrough bleeding and spotting.