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Hypersensitivity to the active substances, to dihydropyridine derivatives or to any of the excipients.
Second and third trimesters of pregnancy.
Severe hepatic insufficiency and biliary obstruction.
The concomitant use of Olmesartan medoxomil plus Amlodipine combination with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR < 60 mL/min/1.73 m2).
Due to the component amlodipine, Olmesartan medoxomil plus Amlodipine combination is also contraindicated in patients with: severe hypotension; shock (including cardiogenic shock); obstruction of the outflow tract of the left ventricle (e.g. high grade aortic stenosis); haemodynamically unstable heart failure after acute myocardial infarction.
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