Allurase: Dosages and Ingredients | Full Prescribing Info

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Full Prescribing Info

Contents

Allopurinol.

Description

Each tablet contains: Allopurinol 100 mg and 300 mg.

Action

Allurase selectively inhibits action of xanthine oxidase, an essential enzyme responsible for synthesis of uric acid thus decreasing urate pool, resorbing tophaceous deposits and ultimately preventing hyperuricosuria.

Indications/Uses

Treatment of gout either primary or secondary to the hyperuricemia associated with blood dyscrasias and their therapy, primary or secondary uric acid nephropathy, with or without accompanying symptoms of gout; recurrent uric acid formation. Allurase is also used in prophylactic treatment to prevent tissue deposition, renal calculi, or uric acid nephropathy in patients with leukemias, lymphomas and malignancies who are receiving cancer chemotherapy with its resultant elevating effect on serum uric acid levels.

Dosage/Direction for Use

Adults: 100 to 200 mg daily in mild conditions.
300 to 600 mg daily in moderately severe conditions.
700 to 900 mg daily in severe conditions.
Children under 15 years: 100 to 400 mg daily.

Contraindications

Generally contraindicated in children except for those with hyperuricemia secondary to malignancy; in pregnant and lactating mothers and in patients with idiopathic hemochromatosis.

Special Precautions

Patients who have developed a severe reaction should not be restarted with the drug. Periodic liver function tests should be performed particularly in patients with pre-existing hepatic and renal diseases.

MIMS Class

Hyperuricemia & Gout Preparations

ATC Classification

M04AA01 - allopurinol ; Belongs to the class of preparations inhibiting uric acid production. Used in the treatment of gout.

Regulatory Classification

Presentation/Packing

Form

Allurase tab 100 mg

Packing/Price

100's (P721/pack)

Form

Allurase tab 300 mg

Packing/Price

50's (P907/blister)

Allurase

allopurinol

Manufacturer:

Terramedic

Distributor:

Metro Drug