Metformin Hydrochloride: Metformin Hydrochloride causes gastrointestinal adverse effects with anorexia, nausea, and vomiting; absorption of various substances including Vitamin B12 may be impaired. Patients may experience a metallic taste and there may be weight loss, which in some diabetics could be an advantage. Hypoglycemia is less of a problem with Metformin Hydrochloride. Lactic acidosis, sometimes fatal, has occurred but to a lesser extent than with Phenformin and it is generally accepted that the lactic acidosis usually occurred in patients whose condition contraindicated the use of Metformin Hydrochloride.
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