Actranex Film-Coated Tablet Dosage/Direction for Use

Adults: Local fibrinolysis: The recommended normal dosage is 15-25 mg/kg body weight (i.e., 2-3 tablets) two to three times daily. For the indications listed as follows, the following doses may be used: Prostatectomy: Prophylaxis and treatment of hemorrhage in high-risk patients should start pre- or post-operatively with the injectable form; followed by 2 tablets three to four times daily until macroscopic hematuria is no longer present.
Menorrhagia: Recommended dosage is 2 tablets 3 times daily as needed for up to 4 days. If there is very heavy menstrual bleeding, consider increasing the dosage. Maximum dose daily is 4 g (8 tablets). Until menstrual bleeding has started, treatment with Tranexamic acid should not be initiated.
Epistaxis: Where recurrent bleeding is anticipated, administer oral therapy (2 tablets three times daily) for 7 days.
Cervix conization: 3 tablets three times daily.
Traumatic hyphema: 2-3 tablets three times daily. The dose is based on 25 mg/kg three times a day.
Hemophilia: For dental extraction management, 2-3 tablets every eight hours. The dose is based on 25 mg/kg.
Hereditary angioneurotic edema: Awareness of the onset of illness are present in some of the patients; advisable treatment for these patients is intermittently 2-3 tablets two to three times daily for some days. Other patients are being treated at this dosage regularly.
Pediatric population: This should be calculated at 25 mg/kg per dose according to body weight. However, there are limited data on efficacy, posology, and safety for these indications.
Elderly: Unless there is evidence of renal failure, the reduction in dosage is unnecessary.
Renal insufficiency: Based on clearance data for the intravenous dosage form, the following oral dosage reduction is indicated for individuals with mild to severe renal insufficiency. (See Table 1.)

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Route of administration: Oral route.