Instructions for Use/Handling: ABEVMY does not contain any antimicrobial preservative; therefore, care must be taken to ensure the sterility of the prepared solution.
ABEVMY is stable in and compatible with sterile saline solution (0.9% sodium chloride solution) for 48 hours under aseptic conditions and 24 hours under standard laboratory conditions at room temperature. From a microbiological point of view, the product should be used immediately.
Administer/mix ABEVMY using normal saline solution only.
Do not prepare or administer in dextrose solution.
ABEVMY must not be administered as an intravenous push or bolus.
To ensure the prepared solution is sterile, a healthcare professional should prepare ABEVMY using aseptic technique.
As with all parenteral medicinal products, ABEVMY should be inspected visually for particulate matter and discolouration prior to administration.
Withdraw the necessary amount of ABEVMY and dilute to the required administration volume with sodium chloride 9 mg/ml (0.9%) solution for injection.
Keep the concentration of the final ABEVMY solution within the range of 1.4 mg/ml to 16.5 mg/ml.
Discard any unused portion left in a vial, as the product contains no preservatives.
ABEVMY is not for intravitreal administration.
Disposal of unused/expired medicines: The release of pharmaceuticals in the environment should be minimized. Medicines should not be disposed of via wastewater and disposal through household waste should be avoided. Use established "collection systems", if available in your location.
Incompatibilities: No incompatibilities have been observed between ABEVMY and polyvinyl chloride or polyolefin bags or infusion sets. Dilute ABEVMY using normal saline solution only. Do not prepare or administer in dextrose solution.
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