Sign Out
Zemimet SR is contraindicated in patients with: hypersensitivity to the active substances or to any of the excipients listed at Description, or a history of serious hypersensitivity reactions, i.e., angioedema or anaphylaxis, to another dipeptidyl peptidase-4 (DPP4) inhibitor.
Patients with congestive heart failure requiring medication.
Any type of acute or chronic metabolic acidosis (such as lactic acidosis, diabetic ketoacidosis).
Diabetic pre-coma.
Known hypersensitivity to components of this drug or biguanides.
Severe renal failure (GFR <30 mL/min).
Acute conditions with the potential to alter renal function such as: dehydration, severe infection, shock, intravascular administration of iodinated contrast agents, any surgical procedures.
Acute or chronic disease which may cause tissue hypoxia such as: cardiac or respiratory failure, recent myocardial infarction, shock.
Debilitated, malnourished, or starved patients, and those with adrenal or pituitary insufficiency.
Hepatic impairment.
Acute alcohol intoxication, alcoholism.
Pulmonary infarction, severe respiratory insufficiency, and any conditions that induce hypoxemia, gastrointestinal symptoms such as diarrhea and vomiting.
Pregnant or potentially pregnant women and breastfeeding women.
Continue with Google