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Hypersensitivity to the active substance, ketamine, or to any of the excipients listed in Description.
Patients for whom an increase in blood pressure or intracranial pressure poses a serious risk (see Adverse Reactions): Patients with aneurysmal vascular disease (including intracranial, thoracic, or abdominal aorta, or peripheral arterial vessels);
Patients with history of intracerebral haemorrhage;
Recent (within 6 weeks) cardiovascular event, including myocardial infarction (MI).
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