Rybelsus Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Semaglutide

Indications/Uses

Adjunct to diet & exercise in adults w/ insufficiently controlled type 2 DM as monotherapy when metformin is inappropriate due to intolerance or CIs; in combination w/ other medicinal products for diabetes.

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Dosage/Direction for Use

Initially 3 mg once daily for 1 mth, may be increased to maintenance dose: 7 mg once daily for at least 1 mth. Then further increased to 14 mg once daily to improve glycaemic control.

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Overdosage

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Administration

Should be taken on an empty stomach: Swallow whole, do not chew/crush/split. Refrain from eating, drinking or taking other oral medications for at least 30 min after intake.

Contraindications

Hypersensitivity.

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Special Precautions

Discontinue use if pancreatitis is suspected. Not to be used in patients w/ type 1 DM or for diabetic ketoacidosis. Not recommended in patients w/ CHF NYHA class IV. Increased risk of hypoglycaemia in combination w/ sulfonylurea or insulin. GI effects; history of pancreatitis; diabetic retinopathy; bariatric surgery. Ensure to avoid fluid depletion. May affect ability to drive & use machines. Not recommended in ESRD. Severe renal & hepatic impairment. Women of childbearing potential should use effective contraception. Not to be used during pregnancy & lactation. Childn & adolescents <18 yr. Elderly ≥75 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Hypoglycaemia; nausea, diarrhoea. Decreased appetite; diabetic retinopathy complications; vomiting, abdominal pain & distension, constipation, dyspepsia, gastritis, GERD, flatulence; fatigue; increased lipase & amylase; dizziness.

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Drug Interactions

Increased AUC of thyroxine. Frequent INR monitoring w/ warfarin or other coumarin derivatives.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Rybelsus detailed prescribing information

Storage

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Description

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Action

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MIMS Class

Antidiabetic Agents

ATC Classification

A10BJ06 - semaglutide ; Belongs to the class of glucagon-like peptide-1 (GLP-1) analogues. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Rybelsus tab 14 mg

Packing/Price

30's;60's;90's

Form

Rybelsus tab 3 mg

Packing/Price

30's;60's;90's

Form

Rybelsus tab 7 mg

Packing/Price

30's;60's;90's

Rybelsus

semaglutide

Manufacturer:

Novo Nordisk

Distributor:

Zuellig Pharma