Nucala Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Mepolizumab

Indications/Uses

Add-on maintenance treatment of severe eosinophilic asthma in patients ≥12 yr. Add-on treatment for relapsing or refractory eosinophilic granulomatosis w/ polyangiitis (EGPA) in adults ≥18 yr. Add-on therapy w/ intranasal corticosteroids for severe chronic rhinosinusitis w/ nasal polyps (CRSwNP) in adults whom therapy w/ systemic corticosteroids &/or surgery provide inadequate disease control.

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Dosage/Direction for Use

SC Severe eosinophilic asthma Adult & adolescent ≥12 yr 100 mg once every 4 wk. EGPA Adult 300 mg once every 4 wk. CRSwNP Adult 100 mg once every 4 wk.

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Overdosage

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Contraindications

Hypersensitivity.

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Special Precautions

Acute & delayed systemic hypersensitivity reactions. Not to be used for acute asthma exacerbations; other eosinophilic conditions or relief of acute bronchospasm or status asthmaticus. Asthma-related adverse events or exacerbations; pre-existing helminth infections. Not recommended to discontinue abruptly. Pregnancy & lactation. Childn <12 yr & adolescents <45 kg w/ severe eosinophilic asthma; childn & adolescents <18 yr w/ EGPA & CRSwNP.

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Use In Pregnancy & Lactation

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Adverse Reactions

Headache. Pharyngitis, lower resp tract infection, UTI; hypersensitivity reactions; nasal congestion; upper abdominal pain; eczema; back pain; pyrexia, inj site- & administration-related reactions.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Nucala detailed prescribing information

Storage

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Description

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Action

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MIMS Class

Antiasthmatic & COPD Preparations

ATC Classification

R03DX09 - mepolizumab ; Belongs to the class of other systemic drugs used in the treatment of obstructive airway diseases.

Regulatory Classification

Presentation/Packing

Form

Nucala soln for inj 100 mg/mL

Packing/Price

(auto-injector) 1's; (safety syringe) 1's

Nucala

mepolizumab

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig Pharma