Noxafil Description

Noxafil MR Tablet: Noxafil 100 mg modified release tablet is a yellow-coated, capsule-shaped tablet debossed with "100" on one side containing 100 mg of posaconazole.
Noxafil Oral Suspension: NOXAFIL ORAL SUSPENSION is a white, cherry flavoured immediate-release oral suspension containing 40 mg of posaconazole per mL.
Posaconazole is a white to off-white crystalline powder. It has a melting range of 164°-165°C and is insoluble in water.
Posaconazole is a broad spectrum triazole antifungal compound with a molecular formula of C₃₇H₄₂F₂N₈O₄ yielding a molecular weight of 700.8.
CAS INDEX NAME: D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydropropyl]-1, 5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl).
CAS RN 171228-49-2.
IUPAC NAME: 4-4-[4-(4-{(3R, 5R)-5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-ylmethyl)tetrahydro-3-furanyl]methoxyphenyl)piperazino]phenyl-1- [(1S,2S)-1-ethyl-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-5-one.
Excipients/Inactive Ingredients: MR Tablet: Hypromellose acetate succinate, microcrystalline cellulose, hydroxypropylcellulose, silicon dioxide, croscarmellose sodium, magnesium stearate, and Opadry II Yellow [consists of the following ingredients: polyvinyl alcohol partially hydrolyzed, Macrogol/PEG 3350 (polyethylene glycol 3350), titanium dioxide (E171), talc, and iron oxide yellow (E172)].
Oral Suspension: Polysorbate 80, simethicone, sodium benzoate, sodium citrate dihydrate, citric acid monohydrate, glycerol, xanthan gum, liquid glucose, titanium dioxide, artificial cherry flavouring, and purified water.