Hexetidine: Uses, Dosage, Side Effects and More

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Mouth/Throat
Aphthous ulcer, Gingivitis, Mouth infections, Oral hygiene, Sore throat

Adult: As 0.1% solution: Rinse or gargle with at least 15 mL of undiluted solution bid or tid. Do not swallow; spit out after use. Treatment recommendations may vary among countries or individual products (refer to local or specific product guidelines).
Child: As 0.1% solution: ≥12 years Same as adult dose.

What are the brands available for Hexetidine in Malaysia?

Bactidol

Other Known Brands

Hexadol

Special Precautions

Not intended to be swallowed. Children. Pregnancy and lactation.

Adverse Reactions

Gastrointestinal disorders: Nausea, vomiting, dry mouth, ageusia, dysphagia, dysgeusia, salivary gland enlargement.
General disorders and administration site conditions: Application site reactions (e.g. irritation, inflammation, blistering, ulceration of mouth or throat, tongue or tooth discolouration, oral paraesthesia).
Immune system disorders: Hypersensitivity reactions.
Respiratory, thoracic and mediastinal disorders: Cough, dyspnoea.
Skin and subcutaneous tissue disorders: Angioedema.

Action

Description:
Mechanism of Action: Hexetidine is a bactericidal and fungicidal antiseptic with broad-spectrum antimicrobial activity against gram-positive and gram-negative bacteria, yeasts (e.g. Candida albicans), and fungi.
Duration: Retention on buccal tissues: 8 to 10 hours (after single oral rinse).

Chemical Structure

Storage

Store below 30°C. Protect from light.

MIMS Class

Preparations for Oral Ulceration & Inflammation

ATC Classification

A01AB12 - hexetidine ; Belongs to the class of local antiinfective and antiseptic preparations. Used in the treatment of diseases of the mouth.

References

Bactidol (Zuellig Pharma). MIMS Malaysia. http://www.mims.com/malaysia. Accessed 03/04/2024.

Buckingham R (ed). Hexetidine. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 03/04/2024.

Hexetidine. UpToDate Lexidrug, Lexi-Drugs Multinational Online. Waltham, MA. UpToDate, Inc. https://online.lexi.com. Accessed 03/04/2024.

Joint Formulary Committee. Hexetidine. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 03/04/2024.

Oraldene (McNeil Products Limited). MHRA. https://products.mhra.gov.uk. Accessed 03/04/2024.

Disclaimer: This information is independently developed by MIMS based on Hexetidine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2025 MIMS. All rights reserved. Powered by MIMS.com