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Hypersensitivity to GnRH, its analogues or to any of the excipients listed in Description (see Adverse Reactions).
3.75 mg: Diphereline P.R. 3.75 mg should never be used during pregnancy and breast feeding. Confirm the patient is not pregnant before starting the treatment.
In the pre-menopausal breast cancer setting: Initiation of aromatase inhibitor treatment before adequate ovarian suppression with triptorelin has been achieved (see Dosage & Administration and Precautions).
11.25 mg: Pregnancy and lactation period.
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