Dienille Contraindications

In the persistence of the following diseases and conditions usage of combined oral contraceptives is contraindicated. In case of first appearance of the diseases as follows while taking combined contraceptive film-coated tablets, its application should be stopped immediately.
Usage of Dienille is contraindicated: hypersensitivity to any of the active ingredients and excipients of the film-coated tablet;
existing venous thrombosis (deep venous thrombosis, pulmonary embolism) or positive patient history;
existing arterial thrombosis (cerebrovascular event, heart attack) or positive patient history or even in the presence of prodromal events (such as angina pectoris, and transient ischemic attack);
in the presence of a severe risk factor or multiple risk factors of arterial thrombosis: diabetes mellitus with vascular involvement; severe hypertension; severe dyslipidaemia; biochemical factors that may be indicative of hereditary or acquired predisposition for venous or arterial thrombosis including activated protein C (APC) resistance, hyperhomocysteinaemia, antithrombin-III deficiency, protein C deficiency, protein S deficiency, antiphospholipid antibodies (anticardiolipin antibodies, lupus anticoagulant);
active severe liver disease or positive patient history for it, if liver function tests have not been normalized yet;
active liver tumor (benign or malignant) or a positive patient history for it;
known or suspected steroid-dependent tumors, (tumors of genital organs or breasts);
vaginal bleeding of unknown origin;
migraine with focal neurological symptoms in the patient history;
pancreatitis or a history thereof if associated with severe hypertriglyceridaemia;
severe renal insufficiency or acute renal failure.
Dienille is contraindicated for concomitant use with the medicinal products containing ombitasvir / paritaprevir / ritonavir and dasabuvir (See Precautions and Interactions).