DBL Potassium Dihydrogen Phosphate Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Presentation/Packing

Concise Prescribing Info

Contents

K dihydrogen phosphate

Indications/Uses

Severe hypophosphataemia (serum levels <0.3 mmol/L) & other degrees of hypophosphataemia when oral therapy is not possible.

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Dosage/Direction for Use

Adult Up to 10 mmol phosphate over 12 hr, may be repeated at 12-hr intervals until serum phosphate exceeds 0.3 mmol/L. Childn 0.15-0.33 mmol/kg over 6 hr, may be repeated at 6-hr intervals until serum phosphate exceeds 0.6 mmol/L. Rate of infusion: Not to exceed 0.2 mmol/kg/hr.

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Overdosage

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Contraindications

Hyperphosphataemia, hypocalcaemia, hyperkalaemia, Addison's disease, urolithiasis, ventricular fibrillation, hyperadrenalism associated w/ adrenogenital syndrome, extensive tissue breakdown eg, severe burns; acute dehydration, heat cramps, increased sensitivity to K administration eg, adynamia episodica hereditaria or congenital paramytonia. Severe renal impairment, renal impairment w/ oliguria & azotaemia.

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Special Precautions

Adrenal insufficiency, diseases associated w/ heart block; hypoparathyroidism, acute dehydration, pancreatitis, rhabdomyolysis, extensive tissue damage eg, severe burns; osteomalacia, rickets, myotonia congenita, heart disease particularly in digitalised patients; hypocalcaemia. Bone binding sites saturation. Monitor serum Na, K, phosphate, Ca conc & renal function every 12-24 hr during therapy. Avoid monobasic K phosphates in hyperkalaemic patients. Not to be administered concomitantly w/ Al, Ca or Mg salts. Chronic renal disease, severe renal insufficiency. Not recommended during pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Hypotension, fluid retention, hyperkalaemia, hypernatraemia, hyperphosphataemia, hypocalcaemia or hypomagnesaemia, extraskeletal calcification eg, nephrocalcinosis in childn.

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Drug Interactions

Hyperkalaemia w/ ACE inhibitors, digitalis glycosides, K-sparing diuretics, NSAIDs, other K-containing medicines. Increased risk of Ca deposition in soft tissues w/ Ca-containing medicines. Hyperphosphataemia w/ other phosphate-containing medicines. Increased salicylates serum conc. Incompatibility w/ Ca-, Mg-, Fe- or Al-containing soln.

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Caution For Usage

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Storage

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Description

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Action

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MIMS Class

Electrolytes

ATC Classification

B05XA06 - potassium phosphate, incl. combinations with other potassium salts ; Belongs to the class of electrolyte solutions used in I.V. solutions.

Presentation/Packing

Form

DBL Potassium Dihydrogen Phosphate inj conc 136.1 mg/mL

Packing/Price

10 mL x 10 × 1's

DBL Potassium Dihydrogen Phosphate

potassium phosphate

Manufacturer:

Pfizer

Distributor:

Zuellig Pharma