Pregnancy: DAKTARIN applied topically are minimally absorbed into the systemic circulation (bioavailability <1%). Although there is no evidence that miconazole is embryotoxic or teratogenic in animals, potential hazards of prescribing DAKTARIN during pregnancy should always be weighed against the expected therapeutic benefits.
Breast-feeding: Topically applied miconazole is minimally absorbed into the systemic circulation, and it is not known whether miconazole is excreted in human breast milk. Caution should be exercised when using topically applied miconazole products during lactation.