Boostrix Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Per 0.5 mL Diphtheria toxoid not <2 IU, tetanus toxoid not <20 IU, Bordetella pertussis antigens (pertussis toxoid 8 mcg, filamentous haemagglutinin 8 mcg, pertactin 2.5 mcg)

Indications/Uses

Booster vaccination against DPT for individuals 4 yr onwards. Passive protection against pertussis in early infancy following maternal immunisation during 2nd- or 3rd-trimester of pregnancy.

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Dosage/Direction for Use

0.5 mL single dose by deep IM inj.

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Overdosage

View Boostrix overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity to vaccine or after previous inj. Encephalopathy of unknown aetiology occurring w/in 7 days following previous vaccination w/ pertussis-containing vaccine. Transient thrombocytopenia or neurological complications following earlier vaccination against diphtheria &/or tetanus.

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Special Precautions

Anaphylactic reaction. Not to be inj IV. Postpone vaccination in patients w/ acute severe febrile illness. Temp ≥40°C; collapse or shock-like state; persistent, inconsolable crying lasting ≥3 hr occurring w/in 48 hr of vaccination; convulsions w/ or w/o fever occurring w/in 3 days of vaccination. Thrombocytopenia or bleeding disorder; history of convulsions, family history of adverse event following vaccination; syncope. Immunosuppressed patients. Pregnancy & lactation. Defer pertussis immunisation in childn w/ progressive neurological disorders.

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Use In Pregnancy & Lactation

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Adverse Reactions

Inj site pain, redness & swelling, fatigue; headache. GI disorders; fever ≥37.5°C. Adults, adolescents & childn ≥10 yr: Malaise. Dizziness; nausea; inj site mass & sterile abscess. Childn 4-9 yr: Irritability; somnolence. Anorexia; diarrhoea, vomiting.

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Drug Interactions

Adequate immunologic response may not be achieved w/ immunosuppressants. Administer at different sites if to be given at the same time w/ other inj vaccine or Ig. Not to be mixed w/ other vaccines in same syringe.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Boostrix detailed prescribing information

Storage

View Boostrix storage conditions for details to ensure optimal shelf-life.

Description

View Boostrix description for details of the chemical structure and excipients (inactive components).

Action

View Boostrix mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Vaccines, Antisera & Immunologicals

ATC Classification

J07AJ52 - pertussis, purified antigen, combinations with toxoids ; Belongs to the class of pertussis bacterial vaccines.

Regulatory Classification

Presentation/Packing

Form

Boostrix susp for inj (pre-filled syringe) 0.5 mL

Packing/Price

0.5 mL x 1's

Boostrix

Manufacturer:

GlaxoSmithKline

Distributor:

Zuellig Pharma