Axcel Lignocaine-P Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Lignocaine/lidocaine 2.5% w/w, prilocaine 2.5% w/w

Indications/Uses

Skin surface anaesth in connection w/ needle insertion, superficial surgical procedures. Surface anaesth of leg ulcers prior to cleaning & superficial surgical procedures eg, fibrin, pus & necroses removal; genital mucosa.

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Dosage/Direction for Use

Apply thick layer w/ occlusive dressing. Adult Needle insertion eg, IV cannula insertion, taking of blood samples Approx 2 g/10 cm² for 1 hr. Max: 5 hr. Minor superficial surgical procedures eg, warts removal 1.5-2 g/10 cm² for 1 hr. Max: 5 hr. More extensive superficial surgical procedures in hospital setting eg, split skin grafting 1.5-2 g/10 cm² for 2 hr. Max: 5 hr. Cleaning of leg ulcers Approx 1-2 g/10 cm² for 30 min, may extend to 60 min for leg ulcers w/ difficult to penetrate tissue. Max: Not >10 g/treatment occasion. Genital mucosa Men 1 g/10 cm² for 15 min. Women 1-2 g/10 cm² for 60 min. Removal of condylomata & prior to local anaesth inj Approx 5-10 g for 5-10 min. No occlusive dressing required. Childn Needle insertion, mollusca removal & other minor superficial surgical procedures Max: 1 g/10 cm². Childn 6-12 yr Max: 20 g/200 cm² for 1 hr up to 5 hr, 1-6 yr Max: 10 g/100 cm² for 1 hr up to 5 hr, 3-12 mth Max: 2 g/20 cm² for 1 hr, 0-3 mth Max: 1 g/10 cm² for not >1 hr. Atopic dermatitis Reduced application time: 30 min.

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Overdosage

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Contraindications

Hypersensitivity to amide-type local anaesth.

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Special Precautions

Not to be applied to open wounds other than leg ulcers & impaired tympanic membrane. Atopic dermatitis. G6PD deficiency, congenital or idiopathic methaemoglobinaemia. Avoid contact w/ eyes. Concomitant use w/ class III antiarrhythmic drugs eg, amiodarone. Monitor results of intracutaneous live vaccines inj eg, BCG. Pregnancy & lactation. Not to be applied to genital mucosa in childn. Not to be used in infants 0-12 mth receiving treatment w/ methaemoglobin-inducing agents; preterm infants w/ gestational age <37 wk. Increased methaemoglobin level in childn/neonates <3 mth.

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Use In Pregnancy & Lactation

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Adverse Reactions

Transient local reactions eg, paleness, erythema (redness) & oedema. Genital mucosa: Local sensations eg, mild burning sensation, itch or warmth.

Drug Interactions

Increased methaemoglobin level w/ methaemoglobin-inducing agents eg, sulphonamides. Increased risk of additive systemic toxicity w/ other local anaesth or structurally-related agents. Reduced clearance of high-dose lidocaine w/ cimetidine or β-blockers.

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Storage

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Description

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Action

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MIMS Class

Anaesthetics - Local & General

ATC Classification

N01BB52 - lidocaine, combinations ; Belongs to the class of amides. Used as local anesthetics.

Regulatory Classification

Presentation/Packing

Form

Axcel Lignocaine-P cream

Packing/Price

5 g x 1's

Axcel Lignocaine-P

lidocaine + prilocaine

Manufacturer:

Kotra Pharma

Distributor:

Kotra Pharma