Gallbladder stone dissolution with ursodeoxycholic acid requires months of therapy. Therefore, caution should be exercised during therapy with ursodeoxycholic acid and alternative therapies should be considered.
Complete dissolution does not occur in all patients and recurrence of stone within 5 years has been observed in up to 50% of patients.
Use in pregnancy & lactation: Ursodeoxycholic acid is not recommended for pregnant and nursing mothers.
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