Triamcort

Triamcinolone

Primary or secondary adrenocorticoid insufficiency, congenital adrenal hyperplasia, non-suppurative thyroiditis, hypercalcemia associated w/ cancer. As adjunctive therapy for short-term use in psoriatic &/or RA (including juvenile RA), ankylosing spondylitis, acute & subacute bursitis, acute non-specific tenosynovitis, acute gouty arthritis, post-traumatic &/or synovitis OA, epicondylitis. Collagen disease during exacerbation or maintenance therapy in SLE, acute rheumatic carditis. Pemphigus, atrophic dermatitis. Allergic conjunctivitis, keratitis, iritis & iridocyclitis, chorioretinitis. Symptomatic sarcoidosis, aspiration pneumonitis. Idiopathic thrombocytopenia purpura & secondary thrombocytopenia in adults, autoimmune hemolytic anemia, RBC anemia, congenital hypoplastic anemia. Leukemia & lymphoma relief in adults, acute leukemia in childn. Nephrotic syndrome w/out uremia, idiopathic or caused by lupus erythematosus. Ulcerative colitis, regional enteritis. Acute exacerbation of brain or spinal cord hardening. Inflammatory reactions in post-op dental & TB meningitis w/ subarachnoid block if given together w/ appropriate anti-TB chemotherapy.

Adult & childn ≥12 yr 4-48 mg daily as single or divided doses. Adrenocorticoid insufficiency 4-12 mg daily as single or divided doses. SLE, acute rheumatic carditis or haematologic disorder Initially 60 mg daily. Childn <12 yr 416 mcg-1.7 mg/kg daily as a single dose or divided doses. Adrenocorticoid insufficiency 117 mcg/kg daily as single dose or multiple doses. Acute leukemia Initially 2 mg/kg/day.

Should be taken with food.

Hypersensitivity to corticosteroids. Systemic fungal infections.

Long-term use causes posterior subcapsular, cataracts, glaucoma & increases secondary ocular infections caused by fungi or viruses. Increased BP, salt & water retention & increased K excretion w/ large doses. Caution in non-specific ulcerative colitis, if there may be perforation of abscesses or other pyogenic infections, diverticulitis, intestinal anastomosis, active or latent peptic ulcers, renal insufficiency, HTN, osteoporosis & myasthenia gravis. Caution in giving corticosteroids to patients w/ ocular herpes simplex because it can cause corneal perforation; w/ ASA to patients w/ hypoprothrombinemia. Monitor growth & development of infants & childn in long-term use of corticosteroids.

Na retention, CHF, HTN, hypokalemic alkalosis, K loss; osteoporosis, steroid myopathy; peptic ulcer accompanied by bleeding & perforation, pancreatitis, abdominal distension & ulcerative esophagitis; hyperpigmentation, acne, purpura stria; convulsions, increased ICP w/ papilledema, vertigo, headache; menstrual changes, decreased carbohydrate tolerance, increased insulin need or oral hypoglycemic drugs in diabetics; posterior subcapsular cataract, increased IOP, glaucoma & exophthalmos; -ve nitrogen balance caused by protein catabolism; anaphylactic reactions.

Corticosteroid Hormones

H02AB08 - triamcinolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.

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