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Treatment of adult patients with hyponatremia secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Treatment of clinically significant hypervolemic hyponatremia that has resisted correction with fluid restriction (serum sodium <125 mEq/L or less-marked hyponatremia that is symptomatic in patients with heart failure).
Important Limitations: Patients requiring intervention to raise serum sodium urgently to prevent or to treat serious neurological symptoms should not be treated with Samsca.
