Adult & childn >12 yr 1-2 g once daily. Severe infection Doses may be increased up to 4 g once daily. Childn ≥50 kg Adult dose. Infant 15 days-12 yr 20-80 mg/kg once daily; 0-14 days 20-50 mg/kg once daily. MeningitisInfant & childn Initially 100 mg/kg once daily. Max: 1 g/day. Gonorrhea 250 mg IM as a single dose. Peri-op prophylaxis 1-2 g as a single dose, 30-90 min before surgery.
Contraindications
Hypersensitivity.
Special Precautions
May cause anaphylactic shock, pseudomembranous colitis, superinfection. Severely impaired kidney & liver function. Pregnancy & lactation. Neonates especially premature babies.
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