PGB

Pregabalin

Peripheral & central neuropathic pain in adults. Generalized anxiety disorders (GAD) in adults. Adjunct therapy in adults w/ partial seizure w/ or w/o secondary generalization.

150-600 mg daily in 2 or 3 divided doses. Neuropathic pain Initially 150 mg daily in 2 or 3 divided doses, can be increased to 300 mg daily after an interval of 3-7 days. May be further increased to a max of 600 mg daily after an additional 1 wk interval if needed. Epilepsy Initially 150 mg daily in 2 or 3 divided doses, can be increased to 300 mg daily after an interval of 7 days. GAD Initially 150 mg daily, can be increased to 300 mg daily after an interval of 1 wk. May increase dose to 450 mg for the next 1 wk. Max of 600 mg daily can be administered after an additional 1 wk interval.

May be taken with or without food.

Hypersensitivity.

Patients w/ hereditary disorders of galactose intolerance, Lapp Lactase deficiency, glucose-galactose malabsorption. Diabetic patients. Avoid abrupt w/drawal. May impair ability to drive or operate machinery. Patients w/ kidney disorders. Pregnancy & lactation. Childn & adolescents. Elderly.

Neutropenia, increased appetite, anorexia, hypoglycemia, psychiatric disorders; hypersensitivity, allergic reactions; neurological & visual disorders; vertigo, hyperacusis; tachycardia, AV block stage 1, sinus tachycardia, bradycardia & arrhythmia, CHF; flushing, hypotension, HTN, peripheral coldness; resp, thorax & mediastinal disorders; GI disorders; skin & SC disorders; musculoskeletal & connective tissue disorders; dysuria, urine incontinence, oliguria, kidney failure, urinary retention; erectile dysfunction, delayed ejaculation, sexual dysfunction, amenorrhea, breast discharge, tenderness & hypertrophy, dysmenorrhea.

May increase the effect of ethanol & lorazepam. CNS depressants. Oxycodone.

Anticonvulsants / Drugs for Neuropathic Pain

N02BF02 - pregabalin ; Belongs to the class of gabapentinoids. Used to relieve pain and other conditions.

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