Therapy should be continued for 24-48 hours after symptoms and fever are reduced. Antacids that contain the same therapeutic aluminium, calcium or magnesium interfere with absorption, and should not be given to patients who are given oral Tetracyclines.
For treatment of streptococcal infections, Tetracycline therapeutic doses given for at least 10 days.
Adults: 200 mg initial dose followed by 100 mg every 12 hours, other alternative if the frequency is more frequent 2-4 x 50 mg capsules as initial dose, followed by 50 mg 4 times daily.
Children above 8 years: 4 mg/kg body weight as the initial dose, followed by 2 mg/kg body weight every 12 hours.
For treatment of Syphilis: the initial dose is given over 10-15 days, the last followed by laboratory tests.
Patients with Gonorrhea who are sensitive to Penicillin, given Minocycline 200 mg as initial dose, followed by 100 mg every 12 hours, a minimum of 4 days with 2-3 days post-therapy culture.
In the treatment of Meningococcal carriers recommended dose of 100 mg every 12 hours for 5 days. In Mycobacterium marinum infections: although the optimal dose has not been determined, but in some cases successfully with 100 mg 2 times a day, for 6-8 weeks.
For treatment of Uncomplicaled Gonococcal Urethritis in males: 100 mg 2 times a day, for 5 days.
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