Dosage: Recommended dosage: one 400 mg film-coated caplet of moxifloxacin once daily.
No dosage adjustment is required for elderly patients.
No dosage adjustment is required for patients with renal failure (CrCl ≤30 mL/min/1.73 m2). For the treatment of skin and soft tissue infections, intravenous therapy should be started, followed by 400 mg moxifloxacin caplets orally.
Drug Administration: The film-coated caplet should be swallowed whole with adequate water and may be taken without food.
Duration of Treatment: For the treatment of the following infections, Moximox film-coated caplet 400 mg should be used for: Acute exacerbation of chronic bronchitis: 5-10 days.
Community-acquired pneumonia: 10 days.
Acute sinusitis: 7 days.
Complicated skin and soft tissue infections: 7-21 days (sequential IV/oral therapy).
Complicated intra-abdominal infections: 5-14 days (sequential IV/oral therapy).
Mild to moderate pelvic inflammatory disease: 14 days.
In clinical trials on patients with complicated skin and soft tissue infections, the intravenous therapy duration was about 6 days, with an average total therapy duration of about 13 days. The dose (400 mg once daily) and duration of therapy should not exceed those recommended.
Missed Dose: If a patient misses one dose, it should be taken as soon as remembered on the same day. If it is close to the time for the next dose, skip the missed dose and take the next dose at the regular time. Do not double the dose to make up for the missed dose.
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