Pharmacology: Midazolam is a relatively short-acting benzodiazepine central nervous system (CNS) depressant, sleep inducting agent for premedication as well as for induction and maintenance of anesthesia. Midazolam has anxiolytic, hypnotic, anticonvulsant, muscle relaxant and anterograde amnestic effect, which are characteristic of benzodiazepines. The mechanism of action of Midazolam is not clearly understood. However, it is probably similar to that of other benzodiazepines. Midazolam activity is primarily due to the parent drug. Elimination of the parent takes places via hepatic metabolism of Midazolam to hydroxylated metabolites that are conjugated and excreted in the urine.
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