Lantus Caution For Usage

SPECIAL PRECAUTIONS FOR DISPOSAL AND OTHER HANDLING: Inspect Lantus before use. It must only be used if the solution is clear, colourless, with no solid particles visible, and if it is of water-like consistency. Since Lantus is a solution, it does not require resuspension before use.
Lantus must not be mixed with any other insulin or diluted. Mixing or diluting can change its time/action profile and mixing can cause precipitation.
Insulin label must always be checked before each injection to avoid medication errors between insulin glargine and other insulins (see Precautions).
Lantus in a cartridge: Insulin pen: Lantus 100 units/ml in cartridges is only suitable for subcutaneous injections from a reusable pen. If administration by syringe is necessary, a vial should be used.
The Lantus cartridges are to be used only in conjunction with the pens: OptiPen, ClickSTAR, Autopen 24, and Allstar.
The pen should be used as recommended in the information provided by the device manufacturer.
The manufacturer's instructions for using the pen must be followed carefully for loading the cartridge, attaching the needle, and administering the insulin injection.
If the insulin pen is damaged or not working properly (due to mechanical defects) it has to be discarded, and a new insulin pen has to be used.
Cartridge: Before insertion into the pen, the cartridge must be stored at room temperature for 1 to 2 hours.
Air bubbles must be removed from the cartridge before injection (see instructions for using the pen).
Empty cartridges must not be refilled.
In-use cartridges: Cartridges in use or carried as a spare may be kept up to four weeks when stored below 30°C. When in use (in the pen), do not store in a refrigerator and protected from heat and light.
After inserting a new cartridge, check to see that the pen is working properly prior to injecting the first dose.
Lantus SoloStar 100 units/ml solution for injection in a pre-filled pen: Lantus SoloStar 100 units/ml in pre-filled pen is only suitable for subcutaneous injections. If administration by syringe is necessary, a vial should be used (see Dosage & Administration and Precautions).
Before first use, the pre-filled pen must be stored at room temperature for 1 to 2 hours. Empty pre-filled pens must never be reused and must be properly discarded. To prevent the possible transmission of disease, each pen must be used by one patient only. Before using the pre-filled pen, the instructions for use must be read carefully.