Lacophen Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Thiamphenicol

Indications/Uses

Resp tract, hepatobiliary, GIT & GUT infections. Typhoid & paratyphoid fever. Gonorrhea.

Dosage/Direction for Use

Adult 500 mg 8 hrly. Childn 30-50 mg/kg/day in 4 divided doses.

Administration

Should be taken on an empty stomach: Take 1 hr before or 2 hr after meals.

Contraindications

Hypersensitivity. Preexisting bone marrow depression or blood dyscrasias. Pregnancy & lactation. Infant.

Special Precautions

Monitor blood counts regularly during prolonged use. Hepatic & renal impairment.

Adverse Reactions

Nausea, vomiting & diarrhea. Reversible bone marrow depression, peripheral & optic neuritis may occur during prolonged use. Less likely to cause Gray syndrome in neonates.

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Drug Interactions

Enhance effects of warfarin & sulfonylureas. Increases plasma conc of phenytoin. Metabolism accelerated by phenobarb & rifampicin.

MIMS Class

Chloramphenicols

ATC Classification

J01BA02 - thiamphenicol ; Belongs to the class of amphenicols. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Lacophen cap 500 mg

Packing/Price

100's (Rp230,000/pak)

Form

Lacophen oral susp 125 mg/5 mL

Packing/Price

60 mL x 1's (Rp12,500/botol)

Lacophen

thiamphenicol

Manufacturer:

Lapi