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Each Glaritus DispoPen-2 contains one 3 mL cartridge of Insulin Glargine injection.
Each mL contains Insulin Glargine 100 IU.
Glaritus contains insulin glargine for subcutaneous use. Insulin glargine is a recombinant human insulin analog that is a long-acting, parenteral blood-glucose-lowering agent. Insulin glargine has low aqueous solubility at neutral pH and completely soluble at pH 4. After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to formation of microprecipitates from which small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration/time profile over 24 hours with no pronounced peak. This profile allows once daily dosing as basal insulin.
Molecular formula: C267H404N72O78S6.
Molecular weight: 6063.
Chemical name: 21A-Gly-30Ba-L-Arg-3030b-L-Arg-human insulin.
