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Fluconazole should not be used in patients with known sensitivity to the drug, any of the inert ingredients or to related azole compounds.
Co-administration of Terfenadine is contraindicated in patients receiving Fluconazole at multiple doses of 400 mg per day or higher. Co-administration of other drugs known to prolong the QT interval and which are metabolised via the enzyme CYP3A4 such as Cisapride, Astemizole, Erythromycin, Pimozide and Quinidine are contraindicated in patients receiving Fluconazole (see Precautions and Interactions).
Co-administration of Cisapride is contraindicated in patients receiving Fluconazole (see Interactions).
