Epivas Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Norepinephrine

Indications/Uses

To control BP in acute hypotension. Adjunctive treatment for cardiac arrest & severe hypotension.

Dosage/Direction for Use

IV Add 4 mL (4 mg) amp to 1,000 mL of 5% dextrose soln. Initially 2-3 mL/min, adjust flow rate to maintain normal BP (80-100 mmHg). Maintenance dose: 0.5-1 mL/min.

Contraindications

Should not be given to potential patients & patients w/ vascular thrombosis. Patients receiving cyclopropane or halogenated hydrocarbon general anesth.

Special Precautions

Patients receiving MAOIs, triptyline or imipramine antidepressants. Avoid HTN. Should be given into a large vein. Extravasation. Carcinogenesis, mutagenesis, impaired fertility. Pregnancy & breastfeeding mothers. Should not be given into the veins of the leg in elderly. Childn. Geriatrics.

Adverse Reactions

Tissue damage due to ischemia, strong vasoconstriction & tissue hypoxia; bradycardia; anxiety; temporary headaches; difficulty breathing; necrosis.

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Drug Interactions

Increased autonomic irritability of the heart w/ cyclopropane & halothane anesth. Co-administration w/ furosemide or other diuretics.

MIMS Class

Vasoconstrictors

ATC Classification

C01CA03 - norepinephrine ; Belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding glycosides. Used in the treatment of hypotension.

Regulatory Classification

Presentation/Packing

Form

Epivas inj 1 mg/mL

Packing/Price

4 mL x 5 × 1's

Epivas

norepinephrine

Manufacturer:

Interbat

Marketer:

Interbat